Common brand names:
This medication contains 2 ingredients: acyclovir and hydrocortisone. It is used to treat cold sores/fever blisters caused by a virus (herpes simplex). Acyclovir is an antiviral medication that works by stopping the growth of the virus. Hydrocortisone is a corticosteroid that helps relieve itching, pain, and burning symptoms. This medication can speed up healing of cold sores, but it does not cure herpes or prevent passing the infection to someone else. It also does not prevent cold sores from returning.
How to Use This Medication
Read the Patient Information Leaflet if available from your pharmacist before you start using this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Use this medication at the first sign of a cold sore. Wash your hands with soap and water before and after applying this medication. Clean and dry the affected area before applying the medication. Apply a thin layer on the affected area as directed by your doctor, usually 5 times a day (every 3 to 4 hours) for 5 days. Apply enough cream to cover all affected areas. Do not rub the area because it may spread to other areas around your mouth or make your cold sore worse. Do not apply other skin products (including make-up, sunscreen, or lip balm) or cover the affected area with a bandage. To prevent washing off the medication, do not bathe, shower, or swim for 30 minutes after application.
Do not apply this medication in the eyes or nose, inside the mouth, or on the genitals.
Cold sores (herpes) can spread easily. Acyclovir/hydrocortisone cream does not prevent the spread of herpes. Avoid sharing eating utensils, cups, razors, or towels during an outbreak. Also, try not to touch the cold sore (including kissing), and wash your hands if you do touch the cold sore.
Use this product regularly to get the most benefit from it. Tell your doctor if your condition persists or worsens after 2 weeks.
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Information expires June 2017.