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Preheat oven to 350 degrees F.
On a cutting board, sprinkle whole brisket with salt and pepper. Place meat in a 9 x 14 x 2-inch baking pan.
In a mixing bowl, mix remaining ingredients and pour over meat. Cover and cook in preheated oven for about 2 hours, or until tender. Slice thin and serve with sauce from pan.

A-Taskit, A-Tisket, It's Annie's Home-Style Brisket